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Paul M O'Neill Selected Research

methsuximide (mesuximide)

10/2018α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy.

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Paul M O'Neill Research Topics

Disease

30Malaria
03/2018 - 02/2004
6Falciparum Malaria (Plasmodium falciparum Malaria)
11/2021 - 11/2005
4COVID-19
03/2022 - 05/2020
4Human Influenza (Influenza)
11/2021 - 01/2018
4Hypersensitivity (Allergy)
01/2020 - 11/2003
3Neoplasms (Cancer)
04/2010 - 02/2004
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
09/2020 - 01/2018
2Toxoplasmosis
03/2020 - 03/2018
2Infections
01/2019 - 02/2014
2Mitochondrial Diseases (Mitochondrial Disease)
03/2016 - 01/2011
2Necrosis
03/2016 - 09/2012
2Drug-Related Side Effects and Adverse Reactions
08/2014 - 11/2003
1Severe Acute Respiratory Syndrome
03/2022
1Hepatitis B
11/2021
1Coronavirus Infections
11/2021
1Virus Diseases (Viral Diseases)
09/2020
1Motor Neuron Disease (Primary Lateral Sclerosis)
01/2020
1Filariasis
01/2019
1Neglected Diseases
01/2019
1Hypermethioninemia
01/2019
1TDP-43 Proteinopathies
10/2018
1Neurodegenerative Diseases (Neurodegenerative Disease)
10/2018
1Hepatocellular Carcinoma (Hepatoma)
03/2016
1Pancreatitis
03/2016
1Chronic Renal Insufficiency
12/2015
1Acute Kidney Injury (Acute Renal Failure)
12/2015
1Kidney Diseases (Kidney Disease)
08/2014
1Multiple Sclerosis
08/2014
1Parasitemia
06/2014
1Leukemia
12/2013
1Lung Neoplasms (Lung Cancer)
05/2013

Drug/Important Bio-Agent (IBA)

18Antimalarials (Antimalarial Agents)IBA
03/2020 - 11/2003
14Pharmaceutical PreparationsIBA
11/2021 - 09/2005
10artemisinin (artemisinine)IBA
11/2021 - 09/2005
4nitazoxanide (NTZ)FDA Link
11/2021 - 01/2018
4EnzymesIBA
09/2020 - 03/2012
4Phosphates (Orthophosphate)IBA
11/2016 - 02/2004
3Antiviral Agents (Antivirals)IBA
03/2022 - 05/2020
3ArtemisininsIBA
05/2013 - 11/2005
3Atovaquone (Mepron)FDA Link
05/2013 - 08/2010
2Antiparasitic Agents (Antiparasitics)IBA
11/2021 - 01/2019
2Cysteine (L-Cysteine)FDA Link
09/2020 - 03/2016
2AnthelminticsIBA
05/2020 - 01/2019
2Peptides (Polypeptides)IBA
03/2020 - 01/2020
2abacavir (Ziagen)FDA Link
01/2020 - 11/2015
2Superoxide Dismutase-1IBA
01/2020 - 01/2018
2Proteins (Proteins, Gene)FDA Link
03/2018 - 03/2012
2Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA
03/2018 - 01/2015
21,2,4-trioxaneIBA
01/2016 - 02/2014
2QuinolonesIBA
05/2013 - 05/2012
2proguanil drug combination atovaquone (malarone)FDA Link
05/2013 - 03/2012
2Electron Transport Complex I (NADH-CoQ Reductase)IBA
03/2012 - 03/2012
2ArtesunateIBA
01/2011 - 09/2005
2IronIBA
11/2010 - 03/2007
1Ivermectin (Mectizan)FDA Link
03/2022
1ElementsIBA
03/2022
1remdesivirIBA
03/2022
1RNA (Ribonucleic Acid)IBA
11/2021
1Peptide Hydrolases (Proteases)FDA Link
09/2020
1SeleniumIBA
09/2020
1tizoxanideIBA
05/2020
1PyrimidinesIBA
03/2020
1QuinolinesIBA
03/2020
1HLA-B57 antigenIBA
01/2020
1ebselenIBA
01/2020
1Anti-Infective Agents (Microbicides)IBA
01/2019
1Methionine (L-Methionine)FDA Link
01/2019
1methsuximide (mesuximide)FDA Link
10/2018
1Cyclophilins (Cyclophilin)IBA
03/2016
1bardoxoloneIBA
03/2016
1Epoxy Compounds (Epoxides)IBA
03/2016
1Mitochondrial Permeability Transition PoreIBA
03/2016
1Quinine (Quinson)FDA Link
01/2016
1Transcription Factors (Transcription Factor)IBA
12/2015
1HLA Antigens (Human Leukocyte Antigens)IBA
11/2015
1MMV008138IBA
04/2015
1Biomarkers (Surrogate Marker)IBA
08/2014
1Dimethyl FumarateIBA
08/2014
1bardoxolone methylIBA
08/2014
18-aminoquinolineIBA
02/2014
1falcipainIBA
09/2013
1Proguanil (Paludrine)FDA Link
05/2013
1CaspasesIBA
09/2012
1Synthetic DrugsIBA
09/2012
1TetraoxanesIBA
09/2012
1LigandsIBA
04/2012
1Cytochromes b (Cytochrome b)IBA
03/2012
17- chloro- 3- methyl- 2- (4- (4- (trifluoromethoxy)benzyl)phenyl)quinolin- 4(1H)- oneIBA
03/2012
1ProdrugsIBA
03/2012
1Oxidoreductases (Dehydrogenase)IBA
03/2012
1SaltsIBA
03/2012
1TetrahydrofolatesIBA
12/2011
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
07/2011
1InsecticidesIBA
07/2011
1Pyrethrins (Pyrethroids)FDA Link
07/2011
1decamethrin (deltamethrin)IBA
07/2011

Therapy/Procedure

7Therapeutics
03/2022 - 11/2016
4Drug Therapy (Chemotherapy)
03/2020 - 11/2004
1Chemoprevention
05/2013
1Oral Administration
03/2012